STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFD74449.1Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II. (498 aa)    
Predicted Functional Partners:
SFE25876.1
Formate dehydrogenase.
    
   0.938
SFE45209.1
Acyl transferase domain-containing protein.
 
 0.848
SFE45142.1
Natural product biosynthesis luciferase-like monooxygenase domain-containing protein.
0.817
SFD74481.1
Predicted dithiol-disulfide isomerase, DsbA family.
       0.816
rplF
Large subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.803
SFD74408.1
Transcriptional regulator, XRE family with cupin sensor.
       0.668
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
   0.663
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.662
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.657
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
   0.657
Your Current Organism:
Sulfitobacter brevis
NCBI taxonomy Id: 74348
Other names: ATCC BAA-4, DSM 11443, JCM 21790, S. brevis, Sulfitobacter brevis Labrenz et al. 2000, strain EL-162
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.