STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE11586.1Glutamate synthase domain-containing protein 2; Belongs to the glutamate synthase family. (538 aa)    
Predicted Functional Partners:
SFE18547.1
Glutamate synthase (NADPH) small subunit.
 
 0.998
SFE18577.1
Glutamate synthase (NADPH) large subunit.
 
0.996
SFD89256.1
2,4-dienoyl-CoA reductase (NADPH2).
 
 0.992
SFD51298.1
Glutamate synthase (NADPH/NADH) small chain.
 
 0.986
SFD47616.1
Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.978
SFD47529.1
Sarcosine oxidase subunit delta.
    
  0.840
SFD47461.1
Sarcosine oxidase subunit gamma.
    
  0.814
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.809
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 0.798
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.749
Your Current Organism:
Sulfitobacter brevis
NCBI taxonomy Id: 74348
Other names: ATCC BAA-4, DSM 11443, JCM 21790, S. brevis, Sulfitobacter brevis Labrenz et al. 2000, strain EL-162
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.