STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE33904.1Methylmalonate-semialdehyde dehydrogenase [acylating]. (499 aa)    
Predicted Functional Partners:
SFE11653.1
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.929
SFE04456.1
propionyl-CoA synthetase.
   
 0.920
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.920
SFD84796.1
Aldehyde dehydrogenase (NAD+).
  
  
 
0.919
SFD74721.1
3-hydroxyisobutyrate dehydrogenase.
  
 
  0.918
SFD84177.1
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
  
 
0.910
SFE91365.1
Biotin carboxyl carrier protein /biotin carboxylase.
   
 
 0.904
SFD85015.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.896
SFE68448.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.879
SFE03966.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase.
  
 0.877
Your Current Organism:
Sulfitobacter brevis
NCBI taxonomy Id: 74348
Other names: ATCC BAA-4, DSM 11443, JCM 21790, S. brevis, Sulfitobacter brevis Labrenz et al. 2000, strain EL-162
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