STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFE27463.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1146 aa)    
Predicted Functional Partners:
SFE04367.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.955
SFE33092.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.951
SFE15714.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
   
 0.938
SFE76003.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.935
SFE68448.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.932
SFE18577.1
Glutamate synthase (NADPH) large subunit.
  
 
 0.924
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.923
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.918
SFD98775.1
L-lactate dehydrogenase (cytochrome).
  
 
 0.915
SFF05325.1
D-lactate dehydrogenase (cytochrome).
  
  
  0.907
Your Current Organism:
Sulfitobacter brevis
NCBI taxonomy Id: 74348
Other names: ATCC BAA-4, DSM 11443, JCM 21790, S. brevis, Sulfitobacter brevis Labrenz et al. 2000, strain EL-162
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.