| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADW21306.1 | relA | TSC_c06790 | TSC_c02480 | Exopolyphosphatase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.917 |
| ADW21306.1 | ribBA | TSC_c06790 | TSC_c09210 | Exopolyphosphatase. | Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.401 |
| gmk | ndk | TSC_c21930 | TSC_c00100 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
| gmk | nrdA | TSC_c21930 | TSC_c12110 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, subunit alpha. | 0.909 |
| gmk | nrdB1 | TSC_c21930 | TSC_c12100 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, subunit beta. | 0.915 |
| gmk | nrdB2 | TSC_c21930 | TSC_c16720 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, subunit beta. | 0.906 |
| gmk | nrdJ1 | TSC_c21930 | TSC_c18760 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.909 |
| gmk | nrdJ2 | TSC_c21930 | TSC_c21530 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.909 |
| gmk | pyk | TSC_c21930 | TSC_c00040 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.921 |
| gmk | relA | TSC_c21930 | TSC_c02480 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.917 |
| gmk | ribBA | TSC_c21930 | TSC_c09210 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.640 |
| ndk | gmk | TSC_c00100 | TSC_c21930 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.927 |
| ndk | nrdA | TSC_c00100 | TSC_c12110 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, subunit alpha. | 0.910 |
| ndk | nrdB1 | TSC_c00100 | TSC_c12100 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, subunit beta. | 0.935 |
| ndk | nrdB2 | TSC_c00100 | TSC_c16720 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, subunit beta. | 0.913 |
| ndk | nrdJ1 | TSC_c00100 | TSC_c18760 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.910 |
| ndk | nrdJ2 | TSC_c00100 | TSC_c21530 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.910 |
| ndk | pyk | TSC_c00100 | TSC_c00040 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.912 |
| ndk | relA | TSC_c00100 | TSC_c02480 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.912 |
| ndk | ribBA | TSC_c00100 | TSC_c09210 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.890 |