STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (261 aa)    
Predicted Functional Partners:
ADW22869.1
Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase.
   
 0.943
ADW22102.1
Ornithine cyclodeaminase.
  
 
 0.926
ADW22868.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.910
ADW21064.1
Proline iminopeptidase.
    
  0.902
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.871
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.831
ADW22317.1
Conserved hypothetical protein.
       0.823
ADW22319.1
16S rRNA M; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.812
ADW22320.1
Stage V sporulation protein S.
       0.782
ADW22655.1
Glutamate synthase, NADPH, large subunit.
     
 0.578
Your Current Organism:
Thermus scotoductus
NCBI taxonomy Id: 743525
Other names: T. scotoductus SA-01, Thermus scotoductus SA-01, Thermus scotoductus str. SA-01, Thermus scotoductus strain SA-01, Thermus sp. SA-01
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.