STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43592.1PFAM: 3-demethylubiquinone-9 3-O-methyltransferase; KEGG: xce:Xcel_0756 3-demethylubiquinone-9 3-methyltransferase. (160 aa)    
Predicted Functional Partners:
AEG45368.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: xce:Xcel_3003 3-demethylubiquinone-9 3-methyltransferase.
 
  
 0.710
AEG43593.1
KEGG: xce:Xcel_0757 exodeoxyribonuclease III Xth; TIGRFAM: Exodeoxyribonuclease III xth; PFAM: Endonuclease/exonuclease/phosphatase.
       0.581
AEG44435.1
PFAM: Domain of unknown function DUF1731, C-terminal; NAD-dependent epimerase/dehydratase; KEGG: nfa:nfa49930 hypothetical protein.
  
    0.573
AEG44382.1
KEGG: xce:Xcel_1687 hypothetical protein.
   
    0.491
AEG45183.1
KEGG: mts:MTES_2737 NADH-flavin reductase.
   
    0.479
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.416
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.416
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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