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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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[Homology]
Score
AEG43593.1KEGG: xce:Xcel_0757 exodeoxyribonuclease III Xth; TIGRFAM: Exodeoxyribonuclease III xth; PFAM: Endonuclease/exonuclease/phosphatase. (270 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.960
AEG43102.1
KEGG: xce:Xcel_3155 exodeoxyribonuclease III Xth; TIGRFAM: Exodeoxyribonuclease III xth; PFAM: Endonuclease/exonuclease/phosphatase.
 
  
 
0.929
AEG42820.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.836
AEG43333.1
KEGG: xce:Xcel_0394 HhH-GPD family protein; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif.
    
 0.788
AEG45599.1
Deoxyribonuclease IV (phage-T(4)-induced); PFAM: Xylose isomerase, TIM barrel domain; KEGG: xce:Xcel_3293 xylose isomerase domain-containing protein; SMART: Endodeoxyribonuclease IV.
    
 
 0.745
AEG44263.1
TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: xce:Xcel_1564 pseudouridine synthase; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RsuA family.
  
    0.735
AEG43097.1
KEGG: xce:Xcel_3180 AraC family transcriptional regulator; PFAM: Ada DNA repair, metal-binding; Helix-turn-helix, AraC type; AlkA, N-terminal; HhH-GPD domain; SMART: Helix-turn-helix, AraC domain; HhH-GPD domain.
   
 0.672
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.636
AEG43928.1
KEGG: xce:Xcel_1142 HhH-GPD family protein; TIGRFAM: Conserved hypothetical protein CHP03252, HhH-GPD; PFAM: HhH-GPD domain.
  
 0.629
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.590
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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