STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43613.1PFAM: DNA helicase, UvrD/REP type; KEGG: xce:Xcel_0780 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1207 aa)    
Predicted Functional Partners:
AEG43617.1
KEGG: xce:Xcel_0786 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; Helicase/RNase D C-terminal, HRDC domain; SMART: Helicase/RNase D C-terminal, HRDC domain.
 
 
0.952
AEG43612.1
PFAM: DNA helicase, UvrD/REP type; KEGG: xce:Xcel_0779 UvrD/REP helicase.
  
0.946
AEG43543.1
KEGG: xce:Xcel_0723 ATP-dependent DNA helicase PcrA; TIGRFAM: DNA helicase, ATP-dependent, PcrA type; PFAM: DNA helicase, UvrD/REP type.
 
 
0.925
recC
Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
  
 
 0.802
AEG43611.1
KEGG: ske:Sked_27680 hypothetical protein.
 
     0.627
AEG44867.1
Membrane-flanked domain DUF304; PFAM: Protein of unknown function DUF304, prokaryotic transmembrane adjacent region; KEGG: xce:Xcel_2360 membrane-flanked domain-containing protein.
 
     0.622
AEG43224.1
KEGG: xce:Xcel_0355 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit; SMART: ATPase, AAA+ type, core.
 
   
 0.616
AEG44934.1
KEGG: xce:Xcel_2407 hypothetical protein.
  
     0.571
recD
Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
  
 
 0.568
AEG45629.1
PFAM: Protein of unknown function DUF1877; KEGG: mil:ML5_4023 hypothetical protein.
  
 
 0.568
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.