STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43616.1KEGG: ske:Sked_27570 glutaredoxin-like protein; TIGRFAM: Glutaredoxin-like protein GlrX; PFAM: Glutaredoxin. (92 aa)    
Predicted Functional Partners:
AEG45002.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.829
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.776
nrdI
Protein nrdI; Probably involved in ribonucleotide reductase function.
  
  
 0.660
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
   
 0.636
AEG43617.1
KEGG: xce:Xcel_0786 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; Helicase/RNase D C-terminal, HRDC domain; SMART: Helicase/RNase D C-terminal, HRDC domain.
     
 0.612
AEG43717.1
LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; KEGG: xce:Xcel_0963 LmbE family protein.
  
   
 0.534
AEG45444.1
KEGG: xce:Xcel_0229 hypothetical protein.
  
   
 0.501
mshA
UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
  
   
 0.476
AEG45054.1
TIGRFAM: Anti-sigma factor RshA; KEGG: xce:Xcel_2491 anti-sigma factor.
  
  
 0.465
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
     0.443
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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