STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (477 aa)    
Predicted Functional Partners:
AEG43743.1
TIGRFAM: Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: xce:Xcel_0988 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.
 
 0.992
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.981
AEG44438.1
KEGG: bcv:Bcav_3565 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.
 
 0.976
mqo
PFAM: Malate:quinone-oxidoreductase; TIGRFAM: Malate:quinone-oxidoreductase; KEGG: xce:Xcel_2241 malate/quinone oxidoreductase; HAMAP: Malate:quinone-oxidoreductase.
    
 0.972
AEG44320.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; KEGG: nca:Noca_2034 malate dehydrogenase.
 
 
 0.957
AEG43745.1
KEGG: ske:Sked_25800 succinate dehydrogenase subunit C; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase, cytochrome b subunit.
   
 
 0.955
AEG43742.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: ske:Sked_25830 succinate dehydrogenase subunit B; PFAM: Ferredoxin; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.950
AEG44437.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: bcv:Bcav_3564 fumarate reductase iron-sulfur subunit; PFAM: Ferredoxin.
  
 0.950
AEG42872.1
PFAM: Lactate/malate dehydrogenase; Amino acid-binding ACT; KEGG: afr:AFE_3000 lactate/malate dehydrogenase family protein.
  
 0.946
AEG43726.1
TIGRFAM: Citrate synthase, type II; KEGG: xce:Xcel_0972 citrate synthase I; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
 0.924
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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