STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43689.1Fructokinase; KEGG: ske:Sked_26450 sugar kinase, ribokinase; PFAM: Carbohydrate/purine kinase. (327 aa)    
Predicted Functional Partners:
AEG44850.1
Fructan beta-fructosidase; PFAM: Glycosyl hydrolases family 32, N-terminal; Glycosyl hydrolase family 32, C-terminal; KEGG: art:Arth_0425 levanase; SMART: Glycoside hydrolase, family 32; Belongs to the glycosyl hydrolase 32 family.
 
 0.982
pfp
Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.915
AEG45132.1
Alpha amylase catalytic region; KEGG: mts:MTES_2158 glycosidase; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region.
 
 
  0.914
pgi
HAMAP: Phosphoglucose isomerase (PGI); KEGG: xce:Xcel_0183 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.910
AEG44849.1
Fructokinase; KEGG: bcv:Bcav_1099 fructokinase; PFAM: Carbohydrate/purine kinase.
  
  
 
0.907
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.906
AEG44842.1
Fructokinase; KEGG: jde:Jden_0744 PfkB domain protein; PFAM: Carbohydrate/purine kinase.
  
  
 
0.906
AEG45099.1
TIGRFAM: Mannose-6-phosphate isomerase, type I; KEGG: xce:Xcel_2543 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I.
    
 0.906
AEG44843.1
KEGG: cfl:Cfla_3401 glycosyl hydrolase family 32 domain protein; PFAM: Glycosyl hydrolases family 32, N-terminal; Glycosyl hydrolase family 32, C-terminal; SMART: Glycoside hydrolase, family 32.
 
 
 0.905
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
  
 
 0.904
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.