STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43848.1TIGRFAM: Peptidase M1, aminopeptidase N actinomycete-type; KEGG: ske:Sked_24580 aminopeptidase N; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal. (855 aa)    
Predicted Functional Partners:
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.923
AEG42879.1
Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase; KEGG: aau:AAur_3482 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase.
     
 0.901
AEG45090.1
KEGG: art:Arth_0896 gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase.
     
 0.901
AEG43499.1
Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
 0.900
AEG44508.1
Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
 0.900
AEG44773.1
Carboxylate-amine ligase ybdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
 0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.841
AEG43861.1
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: xce:Xcel_1111 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.807
AEG45579.1
Cystathionine beta-lyase; KEGG: sco:SCO0731 transferase; PFAM: Aminotransferase, class I/II.
     
  0.800
AEG43850.1
Neprilysin; KEGG: xce:Xcel_1104 neprilysin; PFAM: Peptidase M13; Peptidase M13, neprilysin, C-terminal.
 
   
 0.775
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.