STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43908.1KEGG: xce:Xcel_2325 hypothetical protein. (759 aa)    
Predicted Functional Partners:
AEG43911.1
Helicase domain-containing protein; Manually curated; PFAM: DNA/RNA helicase, C-terminal; SNF2-related; KEGG: gob:Gobs_3743 helicase domain-containing protein; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal.
 
   
 0.948
AEG43909.1
DEAD/DEAH box helicase domain protein; KEGG: gob:Gobs_3741 hypothetical protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Protein of unknown function DUF1998; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
 
     0.947
AEG43910.1
KEGG: saq:Sare_3087 hypothetical protein.
 
     0.947
AEG43906.1
PFAM: 5-methylcytosine restriction system component-like protein; KEGG: ica:Intca_1488 5-methylcytosine restriction system component-like protein.
       0.814
AEG43907.1
KEGG: ica:Intca_1487 ATPase associated with various cellular activities AAA_5; PFAM: ATPase associated with various cellular activities, AAA-5; SMART: ATPase, AAA+ type, core.
       0.814
AEG43664.1
KEGG: xce:Xcel_2129 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; BRCT; SMART: Exonuclease.
  
  
 0.751
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.736
AEG42820.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.695
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
  
 
 0.695
AEG44079.1
TIGRFAM: DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; KEGG: xce:Xcel_1305 RecQ family ATP-dependent DNA helicase; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
 
 
 0.670
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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