STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG43951.1PFAM: Nitrogen regulatory protein PII; KEGG: xce:Xcel_1163 nitrogen regulatory protein P-II. (112 aa)    
Predicted Functional Partners:
AEG43950.1
KEGG: jde:Jden_0980 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
 
 0.999
AEG43952.1
Metal dependent phosphohydrolase; PFAM: PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase; Protein of unknown function DUF294, nucleotidyltransferase putative; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: xce:Xcel_1164 UTP-GlnB uridylyltransferase, GlnD; SMART: Metal-dependent phosphohydrolase, HD region.
 
 
 0.999
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.893
AEG44118.1
KEGG: xce:Xcel_1337 hypothetical protein.
    
 
 0.882
AEG44609.1
TIGRFAM: Glutamine synthetase type I; KEGG: xce:Xcel_2038 glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
 
  
 0.849
AEG44225.1
KEGG: xce:Xcel_1503 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
  
  
 0.841
AEG44612.1
TIGRFAM: Glutamine synthetase type I; KEGG: xce:Xcel_2047 glutamine synthetase; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp.
  
  
 0.790
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
 
 
 0.738
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.721
AEG43954.1
PFAM: Amidohydrolase 1; KEGG: xce:Xcel_1166 amidohydrolase.
       0.695
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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