STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1096 aa)    
Predicted Functional Partners:
AEG44174.1
KEGG: xce:Xcel_1439 hypothetical protein.
 
  
 0.980
AEG44175.1
PFAM: DNA-repair protein, UmuC-like; KEGG: xce:Xcel_1440 hypothetical protein.
 
  
 0.979
AEG44730.1
KEGG: xce:Xcel_2208 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
  
 
 0.883
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.862
AEG42820.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.861
AEG45676.1
KEGG: xce:Xcel_3354 single-strand binding protein; TIGRFAM: Single-strand DNA-binding; PFAM: Primosome PriB/single-strand DNA-binding.
 
 
 
 0.810
AEG45432.1
TIGRFAM: DNA polymerase III, subunit gamma/ tau; PFAM: ATPase, AAA-type, core; KEGG: xce:Xcel_0254 DNA polymerase III subunits gamma and tau; SMART: ATPase, AAA+ type, core.
 
 
 0.795
AEG43664.1
KEGG: xce:Xcel_2129 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; BRCT; SMART: Exonuclease.
  
 
 0.769
AEG43224.1
KEGG: xce:Xcel_0355 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit; SMART: ATPase, AAA+ type, core.
  
 
 0.764
AEG43837.1
KEGG: xce:Xcel_1088 single-strand binding protein; TIGRFAM: Single-strand DNA-binding; PFAM: Primosome PriB/single-strand DNA-binding.
   
 
 0.752
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.