STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (373 aa)    
Predicted Functional Partners:
AEG43263.1
Fructuronate reductase; KEGG: xce:Xcel_2666 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase, C-terminal; Mannitol dehydrogenase, N-terminal.
 
 0.948
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
  
  
 
0.917
AEG43261.1
KEGG: ske:Sked_05310 glucuronate isomerase; PFAM: Uronate isomerase.
 
  
 0.854
AEG43252.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: ske:Sked_27180 sugar kinase, ribokinase.
 
  
 0.852
AEG43851.1
TIGRFAM: Ribose 5-phosphate isomerase, actinobacteria; Ribose/galactose isomerase; KEGG: ske:Sked_24510 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase.
   
 
  0.819
AEG42821.1
6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase related protein; KEGG: xce:Xcel_0003 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; 6-phosphogluconate dehydrogenase, C-terminal.
    
  0.807
AEG44344.1
TIGRFAM: Ribulose-phosphate 3-epimerase; KEGG: xce:Xcel_1725 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
  0.800
AEG44503.1
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
AEG44772.1
PFAM: Polyketide cyclase/dehydrase; KEGG: nfa:nfa2750 hypothetical protein.
       0.522
AEG43251.1
TIGRFAM: KDPG/KHG aldolase; KEGG: xce:Xcel_0907 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG/KHG aldolase.
 
   
 0.446
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.