Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEG44865.1KEGG: xce:Xcel_2358 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR, C-terminal; Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal. (239 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.751
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.706
AEG43250.1
KEGG: xce:Xcel_0906 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR, N-terminal; Transcriptional regulator IclR, C-terminal; SMART: Transcriptional regulator IclR, N-terminal.
  
     0.697
AEG44651.1
KEGG: xce:Xcel_2131 hypothetical protein.
  
     0.669
AEG44667.1
Transcriptional regulator, IclR family; KEGG: mts:MTES_0650 transcriptional regulator; PFAM: Transcriptional regulator IclR, N-terminal; SMART: Transcriptional regulator IclR, N-terminal.
  
     0.531
AEG42827.1
KEGG: xce:Xcel_0008 putative FHA domain containing protein.
  
     0.497
AEG44538.1
KEGG: xce:Xcel_1931 hypothetical protein.
  
     0.484
AEG44866.1
KEGG: xce:Xcel_2359 hypothetical protein.
       0.478
AEG44867.1
Membrane-flanked domain DUF304; PFAM: Protein of unknown function DUF304, prokaryotic transmembrane adjacent region; KEGG: xce:Xcel_2360 membrane-flanked domain-containing protein.
       0.427
AEG44392.1
TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: xce:Xcel_1680 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Anticodon-binding.
  
   
 0.415
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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