STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG44934.1KEGG: xce:Xcel_2407 hypothetical protein. (342 aa)    
Predicted Functional Partners:
AEG42883.1
KEGG: xce:Xcel_0051 methylenetetrahydrofolate reductase (NAD(P)H); PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.757
AEG44545.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.728
AEG43612.1
PFAM: DNA helicase, UvrD/REP type; KEGG: xce:Xcel_0779 UvrD/REP helicase.
  
 
   0.710
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.689
AEG43549.1
KEGG: xce:Xcel_0736 PE-PGRS family protein.
  
     0.688
AEG45104.1
TIGRFAM: Conserved hypothetical protein CHP03089; KEGG: xce:Xcel_2550 hypothetical protein.
 
    0.679
AEG45150.1
PFAM: Protein of unknown function DUF2505; Polyketide cyclase/dehydrase; KEGG: xce:Xcel_2610 hypothetical protein.
 
     0.670
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
     0.652
AEG44867.1
Membrane-flanked domain DUF304; PFAM: Protein of unknown function DUF304, prokaryotic transmembrane adjacent region; KEGG: xce:Xcel_2360 membrane-flanked domain-containing protein.
  
     0.639
AEG45101.1
PFAM: Protein of unknown function DUF1025; KEGG: xce:Xcel_2545 hypothetical protein.
  
     0.625
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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