STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-4Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (82 aa)    
Predicted Functional Partners:
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.900
AEG43805.1
KEGG: xce:Xcel_1050 hypothetical protein.
  
     0.772
AEG44331.1
SMART: HTH transcriptional regulator, MerR; KEGG: xce:Xcel_1741 MerR family transcriptional regulator.
  
     0.771
AEG43962.1
PFAM: Protein of unknown function DUF2469; KEGG: xce:Xcel_1174 hypothetical protein.
  
     0.766
nucS
UPF0286 protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.724
AEG43837.1
KEGG: xce:Xcel_1088 single-strand binding protein; TIGRFAM: Single-strand DNA-binding; PFAM: Primosome PriB/single-strand DNA-binding.
  
     0.710
AEG43352.1
PFAM: Phosphoglycerate mutase; KEGG: xce:Xcel_0443 phosphoglycerate mutase.
  
     0.708
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.701
AEG44251.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.697
AEG45683.1
TIGRFAM: tRNA adenylyltransferase; HDIG; PFAM: Polynucleotide adenylyltransferase region; Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: xce:Xcel_3362 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
     0.677
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.