STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG45157.1TIGRFAM: PAS; PFAM: PAS fold-4; Helix-turn-helix, AraC type; KEGG: bcv:Bcav_2851 transcriptional regulator with PAS/PAC sensors, AraC family; SMART: Helix-turn-helix, AraC domain. (256 aa)    
Predicted Functional Partners:
AEG45156.1
PFAM: Aldehyde dehydrogenase; Proline dehydrogenase; KEGG: xce:Xcel_2617 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
   
 0.683
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.674
AEG45158.1
PFAM: BioY protein; KEGG: sma:SAV_5421 biotin synthase.
       0.474
AEG44133.1
KEGG: bcv:Bcav_4031 protein of unknown function DUF308 membrane.
  
    0.467
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
  
 0.448
AEG43780.1
KEGG: kra:Krad_4012 LysR family transcriptional regulator; TIGRFAM: Transcriptional regulator, ArgP; PFAM: HTH transcriptional regulator, LysR; Belongs to the LysR transcriptional regulatory family.
   
  
 0.416
AEG45129.1
KEGG: ske:Sked_08560 cell envelope-related transcriptional attenuator domain-containing protein; TIGRFAM: Cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator.
   
    0.412
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.