STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG45432.1TIGRFAM: DNA polymerase III, subunit gamma/ tau; PFAM: ATPase, AAA-type, core; KEGG: xce:Xcel_0254 DNA polymerase III subunits gamma and tau; SMART: ATPase, AAA+ type, core. (1188 aa)    
Predicted Functional Partners:
AEG42820.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.994
AEG44730.1
KEGG: xce:Xcel_2208 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
 
 
 0.990
AEG44071.1
DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: xce:Xcel_1296 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type.
 
 0.980
AEG43664.1
KEGG: xce:Xcel_2129 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; BRCT; SMART: Exonuclease.
  
 0.973
AEG43507.1
KEGG: xce:Xcel_0688 exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease.
   
 0.964
AEG44565.1
DNA polymerase III, epsilon subunit; SMART: Exonuclease; Excinuclease ABC, C subunit, N-terminal; TIGRFAM: DNA polymerase III, epsilon subunit; KEGG: xce:Xcel_2004 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; Excinuclease ABC, C subunit, N-terminal.
  
 0.941
AEG43224.1
KEGG: xce:Xcel_0355 DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit; SMART: ATPase, AAA+ type, core.
  
  
 
0.921
AEG45431.1
PFAM: NUDIX hydrolase domain; KEGG: msm:MSMEG_4488 hydrolase, NUDIX family protein.
  
 
 0.807
dnaE2
Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
 
 0.795
AEG43837.1
KEGG: xce:Xcel_1088 single-strand binding protein; TIGRFAM: Single-strand DNA-binding; PFAM: Primosome PriB/single-strand DNA-binding.
   
 
 0.764
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.