STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEG45625.15'-nucleotidase; KEGG: nca:Noca_2321 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; Belongs to the 5'-nucleotidase family. (707 aa)    
Predicted Functional Partners:
AEG43145.1
Endonuclease/exonuclease/phosphatase; KEGG: xce:Xcel_3091 5'-nucleotidase domain-containing protein; PFAM: Endonuclease/exonuclease/phosphatase; Carbohydrate-binding domain, family 5/12; SMART: Carbohydrate-binding domain, family 5/12.
  
 0.994
AEG44686.1
KEGG: kra:Krad_4241 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; Belongs to the 5'-nucleotidase family.
  
  
 
0.927
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.926
tdk-2
HAMAP: Thymidine kinase, subgroup; KEGG: xce:Xcel_2265 thymidine kinase; PFAM: Thymidine kinase.
 
  
  0.922
AEG44512.1
IMP dehydrogenase family protein; SMART: Cystathionine beta-synthase, core; TIGRFAM: IMP dehydrogenase related 1; KEGG: xce:Xcel_1899 IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core.
    
 0.917
AEG43761.1
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.914
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.913
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.911
AEG44200.1
PFAM: Survival protein SurE-like phosphatase/nucleotidase; KEGG: xce:Xcel_2766 survival protein SurE.
     
 0.910
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.909
Your Current Organism:
Isoptericola variabilis
NCBI taxonomy Id: 743718
Other names: I. variabilis 225, Isoptericola variabilis 225, Isoptericola variabilis str. 225, Isoptericola variabilis strain 225
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