node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADV26098.1 | ADV26288.1 | Psesu_0236 | Psesu_0429 | PFAM: O-antigen polymerase; KEGG: xcv:XCV3922 putative cell surface polysaccharide polymerase/ligase. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.911 |
ADV26288.1 | ADV26098.1 | Psesu_0429 | Psesu_0236 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | PFAM: O-antigen polymerase; KEGG: xcv:XCV3922 putative cell surface polysaccharide polymerase/ligase. | 0.911 |
ADV26288.1 | ADV26920.1 | Psesu_0429 | Psesu_1070 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | 0.876 |
ADV26288.1 | ADV28710.1 | Psesu_0429 | Psesu_2886 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | PFAM: lipid A biosynthesis acyltransferase; KEGG: xca:xccb100_3919 lipid A biosynthesis lauroyl acyltransferase. | 0.961 |
ADV26288.1 | kdkA | Psesu_0429 | Psesu_2026 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonic-acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | 0.990 |
ADV26288.1 | kdsB | Psesu_0429 | Psesu_1320 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.984 |
ADV26288.1 | lpxA | Psesu_0429 | Psesu_0788 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.849 |
ADV26288.1 | lpxB | Psesu_0429 | Psesu_0787 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.852 |
ADV26288.1 | lpxC | Psesu_0429 | Psesu_0645 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.849 |
ADV26288.1 | lpxK | Psesu_0429 | Psesu_1319 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
ADV26288.1 | lpxL | Psesu_0429 | Psesu_0428 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.987 |
ADV26920.1 | ADV26288.1 | Psesu_1070 | Psesu_0429 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.876 |
ADV26920.1 | ADV28710.1 | Psesu_1070 | Psesu_2886 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | PFAM: lipid A biosynthesis acyltransferase; KEGG: xca:xccb100_3919 lipid A biosynthesis lauroyl acyltransferase. | 0.637 |
ADV26920.1 | kdsB | Psesu_1070 | Psesu_1320 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.903 |
ADV26920.1 | lpxA | Psesu_1070 | Psesu_0788 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.822 |
ADV26920.1 | lpxB | Psesu_1070 | Psesu_0787 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.832 |
ADV26920.1 | lpxC | Psesu_1070 | Psesu_0645 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.827 |
ADV26920.1 | lpxK | Psesu_1070 | Psesu_1319 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.883 |
ADV26920.1 | lpxL | Psesu_1070 | Psesu_0428 | TIGRFAM: KpsF/GutQ family protein; KEGG: xal:XALc_2135 putative sugar phosphate isomerase involved in capsule formation, KpsF/gutq protein; PFAM: sugar isomerase (SIS); CBS domain containing protein. | Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). | 0.703 |
ADV28710.1 | ADV26288.1 | Psesu_2886 | Psesu_0429 | PFAM: lipid A biosynthesis acyltransferase; KEGG: xca:xccb100_3919 lipid A biosynthesis lauroyl acyltransferase. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.961 |