STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV27090.1PFAM: Aldehyde Dehydrogenase; KEGG: sml:Smlt2132 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)    
Predicted Functional Partners:
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.935
ADV27831.1
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: xcb:XC_2975 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; region: 3HCDH; pfam00725; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.925
ADV27945.1
PFAM: Aldehyde Dehydrogenase; KEGG: xal:XALc_2105 putative aldehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.924
ADV28574.1
KEGG: sml:Smlt3978 putative alcohol dehydrogenase class-III; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.918
ADV27950.1
KEGG: azl:AZL_b01030 methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase.
  
  
 
0.916
ADV26316.1
TIGRFAM: succinate CoA transferase; KEGG: bxe:Bxe_B0397 acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase.
  
 
 0.907
ADV28194.1
PFAM: acylphosphatase; KEGG: tgr:Tgr7_2243 acylphosphatase.
     
 0.903
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.902
ADV26628.1
KEGG: smt:Smal_3034 hypothetical protein.
     
  0.900
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
  0.900
Your Current Organism:
Pseudoxanthomonas suwonensis 111
NCBI taxonomy Id: 743721
Other names: P. suwonensis 11-1, Pseudoxanthomonas suwonensis 11-1, Pseudoxanthomonas suwonensis str. 11-1, Pseudoxanthomonas suwonensis strain 11-1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.