STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV28295.1KEGG: smt:Smal_0488 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein. (458 aa)    
Predicted Functional Partners:
ADV28294.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sml:Smlt0617 putative cystathionine beta/gamma-lyase.
 
 0.997
ADV26612.1
O-succinylhomoserine (thiol)-lyase; KEGG: xcb:XC_1252 catalytic residue; other site; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
 
 0.992
ADV28484.1
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: rmr:Rmar_0184 cystathionine gamma-synthase.
 
 0.992
ADV26431.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: xca:xccb100_1126 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
 
 0.950
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.949
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.938
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.931
ADV26301.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: xcb:XC_0838 catalytic residue; other site.
    
0.929
cysN
Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.928
ADV26514.1
KEGG: spc:Sputcn32_2616 HAD family hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase.
    
 0.918
Your Current Organism:
Pseudoxanthomonas suwonensis 111
NCBI taxonomy Id: 743721
Other names: P. suwonensis 11-1, Pseudoxanthomonas suwonensis 11-1, Pseudoxanthomonas suwonensis str. 11-1, Pseudoxanthomonas suwonensis strain 11-1
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