STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macB_1Macrolide export ATP-binding/permease protein MacB; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. (1084 aa)    
Predicted Functional Partners:
CUO02669.1
Acidobacterial duplicated orphan permease.
 
 
 0.996
macA
Macrolide-specific efflux protein macA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.980
CUO00035.1
FtsX-like permease family.
 
 
 0.721
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.632
CUN91944.1
Acidobacterial duplicated orphan permease.
 
 
 0.618
dus_2
Probable tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.617
macB_5
Macrolide export ATP-binding/permease protein MacB.
 
 
0.591
artM_3
Arginine transport ATP-binding protein ArtM.
 
 
0.588
macB_2
Macrolide export ATP-binding/permease protein MacB.
 
 
0.578
CUN69882.1
Uncharacterised protein.
 
    0.572
Your Current Organism:
Collinsella aerofaciens
NCBI taxonomy Id: 74426
Other names: ATCC 25986, Bacteroides aerofaciens, C. aerofaciens, CCUG 28087, DSM 3979, Eubacterium aerofaciens, JCM 10188, NCTC 11838, Pseudobacterium aerofaciens
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