STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (154 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase.
  
  
 0.999
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 0.996
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
  
 
 0.985
purF
Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
 0.961
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
  
 0.958
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
 0.933
purH
Bifunctional purine biosynthesis protein PurH.
 
  
 0.904
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.862
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
  
  
 0.687
CUN75045.1
Sortase (surface protein transpeptidase).
       0.674
Your Current Organism:
Collinsella aerofaciens
NCBI taxonomy Id: 74426
Other names: ATCC 25986, Bacteroides aerofaciens, C. aerofaciens, CCUG 28087, DSM 3979, Eubacterium aerofaciens, JCM 10188, NCTC 11838, Pseudobacterium aerofaciens
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