STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ18287.1UPF0303 protein; Belongs to the UPF0303 family. (159 aa)    
Predicted Functional Partners:
AEJ18288.1
Hypothetical protein.
       0.762
AEJ18289.1
Protein of unknown function DUF1498.
       0.561
AEJ18290.1
Integral membrane sensor signal transduction histidine kinase.
       0.561
AEJ18291.1
Two component transcriptional regulator, LuxR family.
       0.561
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.499
AEJ18292.1
Extracellular solute-binding protein family 1.
       0.449
AEJ18293.1
Periplasmic binding protein/LacI transcriptional regulator.
       0.449
AEJ18294.1
Periplasmic binding protein/LacI transcriptional regulator.
 
     0.415
AEJ18285.1
Protein of unknown function DUF218.
       0.403
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
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