Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ18398.1Phage shock protein A, PspA. (232 aa)    
Predicted Functional Partners:
AEJ18399.1
Hypothetical protein.
 
     0.925
AEJ18714.1
Signal transduction histidine kinase.
    
 
 0.856
AEJ18897.1
Two component transcriptional regulator, LuxR family.
    
 
 0.759
AEJ20481.1
Hpt sensor hybrid histidine kinase.
    
 
 0.759
AEJ20753.1
Diguanylate cyclase with PAS/PAC sensor.
    
 
 0.754
AEJ18353.1
Integral membrane sensor signal transduction histidine kinase.
   
 
 0.732
AEJ18366.1
PAS/PAC sensor hybrid histidine kinase.
    
 
 0.732
AEJ20844.1
Putative PAS/PAC sensor protein.
    
 
 0.732
AEJ18400.1
Anti-sigma-factor antagonist.
       0.670
AEJ18397.1
Response regulator receiver protein.
     
 0.630
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
Server load: low (38%) [HD]