STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ19742.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)    
Predicted Functional Partners:
AEJ19236.1
Aconitate hydratase.
  
 0.991
AEJ20736.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
   
 
 0.957
AEJ19336.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.945
AEJ19770.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.922
AEJ20735.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin).
   
 
 0.915
AEJ20734.1
2-oxoglutarate synthase.
     
 0.913
AEJ20733.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit.
     
 0.911
AEJ19996.1
Glutamate synthase (ferredoxin).
    
 0.901
AEJ19084.1
Glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.893
AEJ18503.1
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.850
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
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