Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ20132.1Integral membrane sensor signal transduction histidine kinase. (588 aa)    
Predicted Functional Partners:
AEJ20133.1
Two component transcriptional regulator, winged helix family.
 
 
 0.964
AEJ18353.1
Integral membrane sensor signal transduction histidine kinase.
 
 
 
 0.911
AEJ20753.1
Diguanylate cyclase with PAS/PAC sensor.
 
 
0.865
AEJ18254.1
Response regulator receiver protein.
 
 
 0.851
AEJ19751.1
Response regulator receiver protein.
 
 
 0.851
AEJ18887.1
Two component transcriptional regulator, winged helix family.
 
 
 0.848
AEJ18921.1
Two component transcriptional regulator, winged helix family.
 
 
 0.848
AEJ18461.1
Response regulator receiver protein.
 
 
 0.847
AEJ20703.1
Two component transcriptional regulator, winged helix family.
 
 
 0.840
AEJ18662.1
Response regulator receiver modulated protein serine/threonine phosphatase.
 
 
 0.821
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
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