STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ20434.1Butyrate--CoA ligase. (572 aa)    
Predicted Functional Partners:
AEJ19770.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.989
AEJ20435.1
Cupin 2 conserved barrel domain protein.
 
 0.987
AEJ20589.1
Pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.967
AEJ20735.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin).
 
 
 0.937
AEJ20734.1
2-oxoglutarate synthase.
 
 
 0.934
AEJ20169.1
Biotin carboxylase.
 
 0.932
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.931
ackA-2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.931
AEJ20771.1
2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.929
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.929
Your Current Organism:
Treponema caldarium
NCBI taxonomy Id: 744872
Other names: Spirochaeta caldaria DSM 7334, Spirochaeta caldaria H1, T. caldarium DSM 7334, Treponema caldaria DSM 7334, Treponema caldaria H1, Treponema caldaria str. DSM 7334, Treponema caldaria strain DSM 7334, Treponema caldarium DSM 7334
Server load: medium (50%) [HD]