STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)    
Predicted Functional Partners:
AGH51029.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
 
 0.940
AGH51030.1
COG1410 Methionine synthase I, cobalamin-binding domain.
    
 0.938
AGH49679.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 0.929
metZ
Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.926
AGH49917.1
COG2873 O-acetylhomoserine sulfhydrylase.
     
 0.921
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.920
AGH49560.1
COG0775 Nucleoside phosphorylase.
    
 0.916
AGH48732.1
COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.908
AGH48467.1
COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.870
AGH48849.1
COG0498 Threonine synthase.
  
 0.870
Your Current Organism:
Sphingomonas sp. MM1
NCBI taxonomy Id: 745310
Other names: S. sp. MM-1, Sphingomonas sp. MM-1
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