STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (1026 aa)    
Predicted Functional Partners:
RSPO2
R-spondin 2.
   
 0.992
RSPO3
R-spondin 3.
   
 0.980
RSPO4
R-spondin 4.
   
 0.971
RNF43
RING finger protein 43.
    
 0.959
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
  
0.959
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
  
0.921
OLFM4
Olfactomedin 4.
    
 
 0.886
BMI1
BMI1 proto-oncogene, polycomb ring finger.
   
  
 0.814
CHGA
Chromogranin A.
      
 0.800
ADGRL3
Adhesion G protein-coupled receptor L3.
    
 
 0.722
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.