Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CES3Carboxylesterase 3/5. (570 aa)    
Predicted Functional Partners:
PON1
Arylesterase / paraoxonase.
   
  
 0.571
WDR43
WD repeat domain 43.
   
 0.535
UTP4
U3 small nucleolar RNA-associated protein 4.
   
 0.504
SDS
L-serine/L-threonine ammonia-lyase.
      
 0.489
WDR75
NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17).
   
  0.477
ENSPTIP00000000972
annotation not available
   
 0.456
ENSPTIP00000001626
annotation not available
   
 0.456
NRXN3
Neurexin-3.
   
 0.456
ENSPTIP00000019364
Neurexin-1-beta.
   
 0.456
NRXN1
Neurexin-1.
   
 0.456
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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