STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRAPGRB2-related adaptor protein. (241 aa)    
Predicted Functional Partners:
ENSPTIP00000000812
annotation not available
    
 0.821
LAT
Linker for activation of T cells.
   
 0.821
MST1R
Macrophage stimulating 1 receptor.
    
 0.821
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.821
GAB1
GRB2 associated binding protein 1.
    
 0.820
ITSN2
Intersectin 2.
     
0.815
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.806
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.774
PLCG2
Phosphatidylinositol phospholipase C, gamma-2.
    
0.742
PTPN6
Protein tyrosine phosphatase, non-receptor type 6.
   
0.714
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.