STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL2Kelch like family member 2. (597 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
    
 0.868
WNK4
WNK lysine deficient protein kinase 4.
    
 
 0.825
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.805
SLC12A3
Solute carrier family 12 (sodium/chloride transporter), member 3.
    
 
 0.715
TULP4
TUB like protein 4.
     
 0.640
CAND1
Cullin associated and neddylation dissociated 1.
     
 0.632
TMA16
Translation machinery associated 16 homolog.
    
 
 0.611
DVL1
Dishevelled segment polarity protein 1.
    
 0.608
WNK3
WNK lysine deficient protein kinase 3.
    
 
 0.580
NANP
N-acetylneuraminic acid phosphatase.
   
 
 0.565
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.