STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KA3Ribosomal protein S6 kinase A3. (698 aa)    
Predicted Functional Partners:
RPS6KA1
Ribosomal protein S6 kinase alpha-1/2/3/6.
  
 
0.697
RINT1
RAD50-interacting protein 1.
    
 0.656
STX18
Syntaxin 18.
   
 0.646
USE1
Unconventional SNARE in the endoplasmic reticulum protein 1.
    
 0.634
RPS6KA2
Ribosomal protein S6 kinase A2.
  
 
 
0.617
MAPK1
Mitogen-activated protein kinase 1/3.
   
0.614
MAPK3
Mitogen-activated protein kinase 1/3.
   
0.614
DMXL1
DmX-like protein.
   
  
 0.607
MAPK7
Mitogen-activated protein kinase 7.
   
0.583
NBAS
Neuroblastoma amplified sequence.
   
 0.579
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.