STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL21A1Collagen type XXI alpha 1 chain. (957 aa)    
Predicted Functional Partners:
COL22A1
Collagen type XXII alpha 1 chain.
  
 
0.839
COL4A6
Collagen type IV alpha 6 chain.
    
0.694
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
   
 0.630
COL17A1
Collagen type XVII alpha 1 chain.
     
0.617
COL8A1
Collagen type VIII alpha 1 chain.
  
0.609
ITGBL1
Integrin subunit beta like 1.
    
 0.579
COL23A1
Collagen type XXIII alpha 1 chain.
     
0.578
SERPINH1
Serpin peptidase inhibitor, clade H, member 1.
   
 0.576
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
 0.572
ENSPTIP00000004938
annotation not available
     
 0.567
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.