STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLX4Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12). (1680 aa)    
Predicted Functional Partners:
LOC102949708
Structure-specific endonuclease subunit SLX1-like.
   
 0.993
EPRS1
Bifunctional glutamyl/prolyl-tRNA synthetase.
  
 0.991
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.987
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.983
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.955
YARS1
Tyrosyl-tRNA synthetase.
  
 0.920
TERF2
Telomeric repeat binding factor 2.
    
 
 0.916
WRN
Werner syndrome ATP-dependent helicase.
   
 0.914
FANCM
Fanconi anemia complementation group M.
   
 0.904
ENSPTIP00000023400
annotation not available
   
 0.883
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.