STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND2BDENN domain-containing protein 2. (1132 aa)    
Predicted Functional Partners:
RAB9B
RAB9B, member RAS oncogene family.
     
 0.839
RHOBTB3
Rho-related BTB domain-containing protein 3.
      
 0.768
AK3
Nucleoside-triphosphate--adenylate kinase.
      
 0.645
RAB35
RAB35, member RAS oncogene family.
    
 0.645
IFT27
Intraflagellar transport protein 27.
    
 0.613
RAB13
RAB13, member RAS oncogene family.
     
 0.574
ITSN2
Intersectin 2.
    
 
 0.566
ITSN1
Intersectin 1.
    
 
 0.553
AVL9
AVL9 cell migration associated.
      
 0.532
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.521
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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