STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHARPINShank-associated RH domain-interacting protein. (378 aa)    
Predicted Functional Partners:
RNF31
E3 ubiquitin-protein ligase RNF31.
    
 0.999
RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1.
   
0.995
RIPK1
Receptor-interacting serine/threonine-protein kinase 1.
   
 0.978
IKBKG
Inhibitor of nuclear factor kappa B kinase subunit gamma.
    
 0.972
SPATA2
Spermatogenesis-associated protein 2.
     
 0.956
TNFRSF1A
Tumor necrosis factor receptor superfamily member 1A.
    
 0.955
XIAP
E3 ubiquitin-protein ligase XIAP.
    
 0.950
TNF
Tumor necrosis factor superfamily, member 2.
    
 0.950
BIRC2
Baculoviral IAP repeat-containing protein 2/3.
    
 0.947
OTULIN
OTU deubiquitinase with linear linkage specificity.
    
 0.936
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.