STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRFN5Leucine-rich repeat and fibronectin type-III domain-containing protein 5. (719 aa)    
Predicted Functional Partners:
PTPRD
Receptor-type tyrosine-protein phosphatase delta.
    
0.981
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2.
   
 0.795
RABEPK
Rab9 effector protein with kelch motifs.
      
 0.765
TRAPPC6B
Trafficking protein particle complex subunit 6.
   
  
 0.744
PNN
Pinin, desmosome associated protein.
      
 0.712
ADGRL3
Adhesion G protein-coupled receptor L3.
    
   0.693
ADGRL2
Adhesion G protein-coupled receptor L2.
    
   0.693
ADGRL1
Adhesion G protein-coupled receptor L1.
    
   0.693
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
   
 0.664
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1.
   
 0.662
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.