STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRCA2Breast cancer 2 susceptibility protein. (3391 aa)    
Predicted Functional Partners:
RAD51
DNA repair protein RAD51.
   
 0.999
BRCA1
Breast cancer type 1 susceptibility protein.
   
 0.999
PALB2
Partner and localizer of BRCA2.
   
 0.999
FANCD2
Fanconi anemia complementation group D2.
   
 0.995
RAD51C
RAD51-like protein 2.
   
 0.993
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.970
BARD1
BRCA1-associated RING domain protein 1.
   
 0.959
RAD51B
RAD51-like protein 1.
   
 0.958
RAD51D
RAD51-like protein 3.
   
 0.951
WRN
Werner syndrome ATP-dependent helicase.
   
 0.920
Your Current Organism:
Panthera tigris
NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.