GZMH protein (Panthera tigris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GZMH

Granzyme H (cathepsin G-like 2). (250 aa)

Predicted Functional Partners:

ELANE

0.747

AGT

0.716

LOC102962235

0.656

MMP9

0.655

LOC102962532

0.648

CD4

0.647

LOC102956672

0.641

LOC102967742

0.637

BID

0.566

ENSPTIP00000016849

0.510

Your Current Organism:

Panthera tigris

NCBI taxonomy Id: 74533
Other names: Amur tiger, P. tigris altaica, Panthera tigris altaica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	GZMH	ENSPTIP00000014578	ENSPTIP00000026557	Angiotensinogen.	Granzyme H (cathepsin G-like 2).	0.716
AGT	MMP9	ENSPTIP00000014578	ENSPTIP00000026070	Angiotensinogen.	Matrix metalloproteinase-9 (gelatinase B).	0.527
BID	GZMH	ENSPTIP00000008365	ENSPTIP00000026557	BH3 interacting domain death agonist.	Granzyme H (cathepsin G-like 2).	0.566
BID	LOC102967742	ENSPTIP00000008365	ENSPTIP00000001294	BH3 interacting domain death agonist.	Caspase 4.	0.563
CD4	GZMH	ENSPTIP00000004027	ENSPTIP00000026557	CD4 molecule.	Granzyme H (cathepsin G-like 2).	0.647
CD4	LOC102967742	ENSPTIP00000004027	ENSPTIP00000001294	CD4 molecule.	Caspase 4.	0.704
CD4	MMP9	ENSPTIP00000004027	ENSPTIP00000026070	CD4 molecule.	Matrix metalloproteinase-9 (gelatinase B).	0.780
ELANE	GZMH	ENSPTIP00000012131	ENSPTIP00000026557	Neutrophil elastase.	Granzyme H (cathepsin G-like 2).	0.747
ELANE	LOC102956672	ENSPTIP00000012131	ENSPTIP00000008208	Neutrophil elastase.	Chymotrypsinogen 2.	0.436
ELANE	MMP9	ENSPTIP00000012131	ENSPTIP00000026070	Neutrophil elastase.	Matrix metalloproteinase-9 (gelatinase B).	0.511
ENSPTIP00000016849	GZMH	ENSPTIP00000016849	ENSPTIP00000026557	annotation not available	Granzyme H (cathepsin G-like 2).	0.510
ENSPTIP00000016849	LOC102962235	ENSPTIP00000016849	ENSPTIP00000007523	annotation not available	Chymotrypsinogen B.	0.524
ENSPTIP00000016849	LOC102962532	ENSPTIP00000016849	ENSPTIP00000008373	annotation not available	Chymotrypsinogen B-like.	0.513
GZMH	AGT	ENSPTIP00000026557	ENSPTIP00000014578	Granzyme H (cathepsin G-like 2).	Angiotensinogen.	0.716
GZMH	BID	ENSPTIP00000026557	ENSPTIP00000008365	Granzyme H (cathepsin G-like 2).	BH3 interacting domain death agonist.	0.566
GZMH	CD4	ENSPTIP00000026557	ENSPTIP00000004027	Granzyme H (cathepsin G-like 2).	CD4 molecule.	0.647
GZMH	ELANE	ENSPTIP00000026557	ENSPTIP00000012131	Granzyme H (cathepsin G-like 2).	Neutrophil elastase.	0.747
GZMH	ENSPTIP00000016849	ENSPTIP00000026557	ENSPTIP00000016849	Granzyme H (cathepsin G-like 2).	annotation not available	0.510
GZMH	LOC102956672	ENSPTIP00000026557	ENSPTIP00000008208	Granzyme H (cathepsin G-like 2).	Chymotrypsinogen 2.	0.641
GZMH	LOC102962235	ENSPTIP00000026557	ENSPTIP00000007523	Granzyme H (cathepsin G-like 2).	Chymotrypsinogen B.	0.656