STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCG33955.1Pyruvate, water dikinase. (864 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.889
SCG52912.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.855
ppc
Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.823
SCG48208.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.821
SCG45342.1
2-oxoisovalerate dehydrogenase E1 component.
    
 0.793
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.765
SCG56705.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
    
 0.763
SCG52921.1
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
 0.761
SCG79123.1
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.753
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.749
Your Current Organism:
Micromonospora humi
NCBI taxonomy Id: 745366
Other names: DSM 45647, JCM 15292, M. humi, Micromonospora humi Songsumanus et al. 2011, Micromonospora sp. P0402, PCU 315, PCU:315, strain P0402
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