STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EU96_1172Phosphoglycerate mutase; Alternative locus ID: PMIT9302_0661; Belongs to the phosphoglycerate mutase family. (442 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.934
EU96_0106
Serine--glyoxylate aminotransferase; Alternative locus ID: PMIT9302_1381.
    
  0.924
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.918
pgk
Phosphoglycerate kinase; Alternative locus ID: PMIT9302_1632; Belongs to the phosphoglycerate kinase family.
     
 0.918
EU96_0531
Serine--pyruvate aminotransferase; Alternative locus ID: PMIT9302_1096; L-alanine:glyoxylate aminotransferase.
    
  0.908
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.826
EU96_1574
D-3-phosphoglycerate dehydrogenase; Alternative locus ID: PMIT9302_0190; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.795
EU96_1096
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Alternative locus ID: PMIT9302_0585; Belongs to the UPF0284 family.
  
 
 0.773
pgi
Glucose-6-phosphate isomerase; Alternative locus ID: PMIT9302_1125; Belongs to the GPI family.
    
 0.751
EU96_0434
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
     
 0.710
Your Current Organism:
Prochlorococcus marinus MIT9302
NCBI taxonomy Id: 74545
Other names: P. marinus str. MIT 9302, Prochlorococcus marinus str. MIT 9302, Prochlorococcus sp. MIT 9302, Prochlorococcus sp. MIT9302
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