STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnP5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (297 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.926
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.771
EU96_1626
Cytosine deaminase; Alternative locus ID: PMIT9302_0242.
    
 0.763
EU96_0985
Putative LysM domain; Alternative locus ID: PMIT9302_0474.
    
  0.693
EU96_1543
D-glycero-D-manno-heptose 1,7-bisphosphate phosphatasee; Alternative locus ID: PMIT9302_0159.
  
 0.692
EU96_1806
Nicotinate-nucleotide adenylyltransferase bacterial NadD family; Alternative locus ID: PMIT9302_0422; Belongs to the NadD family.
    
 0.689
EU96_0239
Putative PURINE PHOSPHORIBOSYLTRANSFERASE related protein; Alternative locus ID: PMIT9302_1964.
    
 0.687
EU96_0532
tRNA-specific adenosine-34 deaminase; Alternative locus ID: PMIT9302_1097.
    
 0.643
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.640
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.637
Your Current Organism:
Prochlorococcus marinus MIT9302
NCBI taxonomy Id: 74545
Other names: P. marinus str. MIT 9302, Prochlorococcus marinus str. MIT 9302, Prochlorococcus sp. MIT 9302, Prochlorococcus sp. MIT9302
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