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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABB49241.1Isochorismate synthase; Alternative locus ID: P9312_01871. (470 aa)    
Predicted Functional Partners:
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
 0.988
ABB50829.1
Conserved hypothetical protein; Alternative locus ID: P9312_19201.
     
 0.905
ABB49238.1
Putative O-succinylbenzoic acid--CoA ligase (OSB-CoA synthetase); Alternative locus ID: P9312_01841.
 
   
 0.887
ABB50730.1
Anthranilate synthase, component I; Alternative locus ID: P9312_18201.
  
  
0.868
menA
1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.848
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
    
 0.831
ABB50718.1
Arogenate dehydrogenase (NADP); Alternative locus ID: P9312_18081.
     
 0.825
ABB49239.1
Putative O-succinylbenzoate synthase; Alternative locus ID: P9312_01851; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
   
 0.816
ABB49735.1
L-aspartate aminotransferase apoenzyme; Alternative locus ID: P9312_07051.
    
  0.802
ABB49250.1
Histidinol phosphate aminotransferase apoenzyme; Alternative locus ID: P9312_01961.
     
  0.800
Your Current Organism:
Prochlorococcus marinus MIT9312
NCBI taxonomy Id: 74546
Other names: P. marinus str. MIT 9312, Prochlorococcus marinus str. MIT 9312, Prochlorococcus sp. MIT 9312, Prochlorococcus sp. MIT9312
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